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Mager Scientific oabr amplitude
A Exemplary oABRs driven with varying radiant flux (1000 × 1 ms at 10 Hz, colors code the radiant flux in mW) of mice injected with AAV‐PHP.B‐vf‐Chrimson (left) or AAV‐PHP.B‐vf‐Chrimson‐ES/TS (right). First positive (P 1 ) and first negative (N 1 ) peaks are indicated by black dots on the waveform triggered upon 41.7 mW radiant flux (the initial negative deflection results from filtering). Vertical scale bar: 1 µV. B Exemplary oABRs driven with varying stimulation rate (1 ms for data points ≤ 500 Hz and 0.5 ms above 500 Hz at 41.7 mW (highest radiant flux), colors code the stimulation rate) of the same animals from (A). Stimuli applied at a rate of 200 Hz and the corresponding P 1 ‐N 1 pairs are indicated by yellow shaded area and black dots, respectively. Vertical scale bar: 1 µV. C oABRs driven with varying light pulse duration (10 Hz at 41.7 mW (highest radiant flux)), colors code the pulse duration) of the same animals from (A). Exemplary pulse duration of 1 ms and corresponding P 1 ‐N 1 pair are indicated by yellow shaded area and black dots. Vertical scale bar: 1 µV. D–I Quantification of P 1 ‐N 1 amplitudes (mean ± SEM) and P 1 latencies (mean ± SEM) as a function of radiant flux (D, E, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 9 mice), stimulation rate (F, G, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 8 mice), and pulse duration (H, I, vf‐Chrimson: N = 10 mice, vf‐Chrimson‐ES/TS: N = 9 mice). The average P 1 ‐N 1 amplitude of f‐Chrimson (green in F and G) is replotted <t>from</t> <t>Mager</t> et al, . Inset in (D), quantification of the <t>oABR</t> threshold. Inset in (E), quantification of the shortest P1 latencies elicited among any radiant flux (****, P ‐value < 10 −4 , Mann–Whitney U ‐test). Inset in (H), quantification of the optimal pulse duration required to elicit the maximum P 1 ‐N 1 amplitude. Boxes show 25th percentile, median, 75th percentile, the black dot the mean, and whiskers maximum and minimum. Source data are available online for this figure.
Oabr Amplitude, supplied by Mager Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/oabr+amplitude/pmc08185542-197-20-26?v=Mager+Scientific
Average 90 stars, based on 1 article reviews
oabr amplitude - by Bioz Stars, 2026-07
90/100 stars

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1) Product Images from "Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway"

Article Title: Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway

Journal: EMBO Molecular Medicine

doi: 10.15252/emmm.202013391

A Exemplary oABRs driven with varying radiant flux (1000 × 1 ms at 10 Hz, colors code the radiant flux in mW) of mice injected with AAV‐PHP.B‐vf‐Chrimson (left) or AAV‐PHP.B‐vf‐Chrimson‐ES/TS (right). First positive (P 1 ) and first negative (N 1 ) peaks are indicated by black dots on the waveform triggered upon 41.7 mW radiant flux (the initial negative deflection results from filtering). Vertical scale bar: 1 µV. B Exemplary oABRs driven with varying stimulation rate (1 ms for data points ≤ 500 Hz and 0.5 ms above 500 Hz at 41.7 mW (highest radiant flux), colors code the stimulation rate) of the same animals from (A). Stimuli applied at a rate of 200 Hz and the corresponding P 1 ‐N 1 pairs are indicated by yellow shaded area and black dots, respectively. Vertical scale bar: 1 µV. C oABRs driven with varying light pulse duration (10 Hz at 41.7 mW (highest radiant flux)), colors code the pulse duration) of the same animals from (A). Exemplary pulse duration of 1 ms and corresponding P 1 ‐N 1 pair are indicated by yellow shaded area and black dots. Vertical scale bar: 1 µV. D–I Quantification of P 1 ‐N 1 amplitudes (mean ± SEM) and P 1 latencies (mean ± SEM) as a function of radiant flux (D, E, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 9 mice), stimulation rate (F, G, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 8 mice), and pulse duration (H, I, vf‐Chrimson: N = 10 mice, vf‐Chrimson‐ES/TS: N = 9 mice). The average P 1 ‐N 1 amplitude of f‐Chrimson (green in F and G) is replotted from Mager et al, . Inset in (D), quantification of the oABR threshold. Inset in (E), quantification of the shortest P1 latencies elicited among any radiant flux (****, P ‐value < 10 −4 , Mann–Whitney U ‐test). Inset in (H), quantification of the optimal pulse duration required to elicit the maximum P 1 ‐N 1 amplitude. Boxes show 25th percentile, median, 75th percentile, the black dot the mean, and whiskers maximum and minimum. Source data are available online for this figure.
Figure Legend Snippet: A Exemplary oABRs driven with varying radiant flux (1000 × 1 ms at 10 Hz, colors code the radiant flux in mW) of mice injected with AAV‐PHP.B‐vf‐Chrimson (left) or AAV‐PHP.B‐vf‐Chrimson‐ES/TS (right). First positive (P 1 ) and first negative (N 1 ) peaks are indicated by black dots on the waveform triggered upon 41.7 mW radiant flux (the initial negative deflection results from filtering). Vertical scale bar: 1 µV. B Exemplary oABRs driven with varying stimulation rate (1 ms for data points ≤ 500 Hz and 0.5 ms above 500 Hz at 41.7 mW (highest radiant flux), colors code the stimulation rate) of the same animals from (A). Stimuli applied at a rate of 200 Hz and the corresponding P 1 ‐N 1 pairs are indicated by yellow shaded area and black dots, respectively. Vertical scale bar: 1 µV. C oABRs driven with varying light pulse duration (10 Hz at 41.7 mW (highest radiant flux)), colors code the pulse duration) of the same animals from (A). Exemplary pulse duration of 1 ms and corresponding P 1 ‐N 1 pair are indicated by yellow shaded area and black dots. Vertical scale bar: 1 µV. D–I Quantification of P 1 ‐N 1 amplitudes (mean ± SEM) and P 1 latencies (mean ± SEM) as a function of radiant flux (D, E, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 9 mice), stimulation rate (F, G, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 8 mice), and pulse duration (H, I, vf‐Chrimson: N = 10 mice, vf‐Chrimson‐ES/TS: N = 9 mice). The average P 1 ‐N 1 amplitude of f‐Chrimson (green in F and G) is replotted from Mager et al, . Inset in (D), quantification of the oABR threshold. Inset in (E), quantification of the shortest P1 latencies elicited among any radiant flux (****, P ‐value < 10 −4 , Mann–Whitney U ‐test). Inset in (H), quantification of the optimal pulse duration required to elicit the maximum P 1 ‐N 1 amplitude. Boxes show 25th percentile, median, 75th percentile, the black dot the mean, and whiskers maximum and minimum. Source data are available online for this figure.

Techniques Used: Injection, MANN-WHITNEY



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Mager Scientific oabr amplitude
A Exemplary oABRs driven with varying radiant flux (1000 × 1 ms at 10 Hz, colors code the radiant flux in mW) of mice injected with AAV‐PHP.B‐vf‐Chrimson (left) or AAV‐PHP.B‐vf‐Chrimson‐ES/TS (right). First positive (P 1 ) and first negative (N 1 ) peaks are indicated by black dots on the waveform triggered upon 41.7 mW radiant flux (the initial negative deflection results from filtering). Vertical scale bar: 1 µV. B Exemplary oABRs driven with varying stimulation rate (1 ms for data points ≤ 500 Hz and 0.5 ms above 500 Hz at 41.7 mW (highest radiant flux), colors code the stimulation rate) of the same animals from (A). Stimuli applied at a rate of 200 Hz and the corresponding P 1 ‐N 1 pairs are indicated by yellow shaded area and black dots, respectively. Vertical scale bar: 1 µV. C oABRs driven with varying light pulse duration (10 Hz at 41.7 mW (highest radiant flux)), colors code the pulse duration) of the same animals from (A). Exemplary pulse duration of 1 ms and corresponding P 1 ‐N 1 pair are indicated by yellow shaded area and black dots. Vertical scale bar: 1 µV. D–I Quantification of P 1 ‐N 1 amplitudes (mean ± SEM) and P 1 latencies (mean ± SEM) as a function of radiant flux (D, E, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 9 mice), stimulation rate (F, G, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 8 mice), and pulse duration (H, I, vf‐Chrimson: N = 10 mice, vf‐Chrimson‐ES/TS: N = 9 mice). The average P 1 ‐N 1 amplitude of f‐Chrimson (green in F and G) is replotted <t>from</t> <t>Mager</t> et al, . Inset in (D), quantification of the <t>oABR</t> threshold. Inset in (E), quantification of the shortest P1 latencies elicited among any radiant flux (****, P ‐value < 10 −4 , Mann–Whitney U ‐test). Inset in (H), quantification of the optimal pulse duration required to elicit the maximum P 1 ‐N 1 amplitude. Boxes show 25th percentile, median, 75th percentile, the black dot the mean, and whiskers maximum and minimum. Source data are available online for this figure.
Oabr Amplitude, supplied by Mager Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/oabr+amplitude/pmc08185542-197-20-26?v=Mager+Scientific
Average 90 stars, based on 1 article reviews
oabr amplitude - by Bioz Stars, 2026-07
90/100 stars
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A Exemplary oABRs driven with varying radiant flux (1000 × 1 ms at 10 Hz, colors code the radiant flux in mW) of mice injected with AAV‐PHP.B‐vf‐Chrimson (left) or AAV‐PHP.B‐vf‐Chrimson‐ES/TS (right). First positive (P 1 ) and first negative (N 1 ) peaks are indicated by black dots on the waveform triggered upon 41.7 mW radiant flux (the initial negative deflection results from filtering). Vertical scale bar: 1 µV. B Exemplary oABRs driven with varying stimulation rate (1 ms for data points ≤ 500 Hz and 0.5 ms above 500 Hz at 41.7 mW (highest radiant flux), colors code the stimulation rate) of the same animals from (A). Stimuli applied at a rate of 200 Hz and the corresponding P 1 ‐N 1 pairs are indicated by yellow shaded area and black dots, respectively. Vertical scale bar: 1 µV. C oABRs driven with varying light pulse duration (10 Hz at 41.7 mW (highest radiant flux)), colors code the pulse duration) of the same animals from (A). Exemplary pulse duration of 1 ms and corresponding P 1 ‐N 1 pair are indicated by yellow shaded area and black dots. Vertical scale bar: 1 µV. D–I Quantification of P 1 ‐N 1 amplitudes (mean ± SEM) and P 1 latencies (mean ± SEM) as a function of radiant flux (D, E, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 9 mice), stimulation rate (F, G, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 8 mice), and pulse duration (H, I, vf‐Chrimson: N = 10 mice, vf‐Chrimson‐ES/TS: N = 9 mice). The average P 1 ‐N 1 amplitude of f‐Chrimson (green in F and G) is replotted from Mager et al, . Inset in (D), quantification of the oABR threshold. Inset in (E), quantification of the shortest P1 latencies elicited among any radiant flux (****, P ‐value < 10 −4 , Mann–Whitney U ‐test). Inset in (H), quantification of the optimal pulse duration required to elicit the maximum P 1 ‐N 1 amplitude. Boxes show 25th percentile, median, 75th percentile, the black dot the mean, and whiskers maximum and minimum. Source data are available online for this figure.

Journal: EMBO Molecular Medicine

Article Title: Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway

doi: 10.15252/emmm.202013391

Figure Lengend Snippet: A Exemplary oABRs driven with varying radiant flux (1000 × 1 ms at 10 Hz, colors code the radiant flux in mW) of mice injected with AAV‐PHP.B‐vf‐Chrimson (left) or AAV‐PHP.B‐vf‐Chrimson‐ES/TS (right). First positive (P 1 ) and first negative (N 1 ) peaks are indicated by black dots on the waveform triggered upon 41.7 mW radiant flux (the initial negative deflection results from filtering). Vertical scale bar: 1 µV. B Exemplary oABRs driven with varying stimulation rate (1 ms for data points ≤ 500 Hz and 0.5 ms above 500 Hz at 41.7 mW (highest radiant flux), colors code the stimulation rate) of the same animals from (A). Stimuli applied at a rate of 200 Hz and the corresponding P 1 ‐N 1 pairs are indicated by yellow shaded area and black dots, respectively. Vertical scale bar: 1 µV. C oABRs driven with varying light pulse duration (10 Hz at 41.7 mW (highest radiant flux)), colors code the pulse duration) of the same animals from (A). Exemplary pulse duration of 1 ms and corresponding P 1 ‐N 1 pair are indicated by yellow shaded area and black dots. Vertical scale bar: 1 µV. D–I Quantification of P 1 ‐N 1 amplitudes (mean ± SEM) and P 1 latencies (mean ± SEM) as a function of radiant flux (D, E, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 9 mice), stimulation rate (F, G, vf‐Chrimson: N = 13 mice, vf‐Chrimson‐ES/TS: N = 8 mice), and pulse duration (H, I, vf‐Chrimson: N = 10 mice, vf‐Chrimson‐ES/TS: N = 9 mice). The average P 1 ‐N 1 amplitude of f‐Chrimson (green in F and G) is replotted from Mager et al, . Inset in (D), quantification of the oABR threshold. Inset in (E), quantification of the shortest P1 latencies elicited among any radiant flux (****, P ‐value < 10 −4 , Mann–Whitney U ‐test). Inset in (H), quantification of the optimal pulse duration required to elicit the maximum P 1 ‐N 1 amplitude. Boxes show 25th percentile, median, 75th percentile, the black dot the mean, and whiskers maximum and minimum. Source data are available online for this figure.

Article Snippet: So far estimates of this so‐called output dynamic range of the activation of the auditory pathway were based either on oABR amplitude (approximately 10–16 dB [mW], Mager et al, ; Wrobel et al, ) or multi‐unit firing rate in the inferior colliculus (approximately 11 dB [mW], Dieter et al, ).

Techniques: Injection, MANN-WHITNEY